A recent study observed that knee joint injections of bone marrow-sourced stem cells alone or in combination with Platelet-rich Plasma (PRP) are safe and have beneficial effects in patients with symptoms of knee osteoarthritis. Patients experienced significant improvements in pain, function, daily living and sports activities based on rating scores at twelve month end-points. The study noted that adding a PRP injection two weeks after the initial stem cell injection in the knee did not appear to add any additional benefit.
These results are encouraging for patients with knee osteoarthritis. The procedure is minimally invasive and does not require hospitalization. This is a Level 2 study, meaning it was prospective and forward looking.
Bastos R. ,et al: Knee Surg Sports Traumatol Arthrosc. 2018 Mar 6, doi: 10:1007/s00167-018-4883-9.